Postnephrectomy outcomes following en bloc resection of primary retroperitoneal sarcoma: multicentre study

Author:

Fairweather Mark12ORCID,Lyu Heather1ORCID,Conti Lorenzo3,Callegaro Dario3,Radaelli Stefano3,Fiore Marco3ORCID,Ng Deanna45,Swallow Carol45,Gronchi Alessandro3,Raut Chandrajit P.12

Affiliation:

1. Department of Surgery, Brigham and Women’s Hospital, Boston, Massachusetts, USA

2. Center for Sarcoma and Bone Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Boston, Massachusetts, USA

3. Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

4. Department of Surgical Oncology, Princess Margaret Cancer Centre and Mount Sinai Hospital, Toronto, Ontario, Canada

5. Department of Surgery, University of Toronto, Toronto, Ontario, Canada

Abstract

This article reports on postoperative renal function in the largest series of patients with primary retroperitoneal sarcoma undergoing nephrectomy at three high-volume sarcoma centres. Although half of patients develop chronic kidney disease of stage 3 or higher, rarely do patients develop acute renal failure requiring renal replacement therapy.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference11 articles.

1. Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control;Bonvalot;Ann Surg Oncol,2010

2. Surgical management of primary retroperitoneal sarcomas: rationale for selective organ resection;Fairweather;Ann Surg Oncol,2018

3. Contiguous organ resection is safe in patients with retroperitoneal sarcoma: an ACS-NSQIP analysis;Tseng;J Surg Oncol,2011

4. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification;National Kidney Foundation;Am J Kidney Dis,2002

5. Long-term morbidity after multivisceral resection for retroperitoneal sarcoma;Callegaro;Br J Surg,2015

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