Role of IL-6 and IL-6 targeted therapy in systemic lupus erythematosus

Author:

Nepal Desh1ORCID,Gazeley David1

Affiliation:

1. Division of Rheumatology, Department of Medicine, Medical College of Wisconsin , Milwaukee, WI, USA

Abstract

Abstract Interleukin-6 (IL-6) is one of the cytokines implicated in murine and human SLE. Only a few small studies have investigated IL-6 inhibition in human SLE. Currently, there are no studies registered in clinicaltrials.gov to assess the IL-6 targeted therapy in SLE, yet its role in the future remains to be defined. This narrative review analyses these and potential areas of future studies with IL-6 targeted therapy in SLE.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Rheumatology

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