Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome-Reference-Cited by-同舟云学术

Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

Published:2019-09-25 Issue:8 Volume:70 Page:1750-1753
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Auld Sara C¹,Maenetje Pholo²,Ravimohan Shruthi³^ORCID,Weissman Drew³,Ncube Itai²,Mlotshwa Mandla²,Ratsela Nelly²,Chase William³,Vangu Mboyo-Di-Tamba⁴,Wallis Robert²,Churchyard Gavin²⁵⁶,Kornfeld Hardy⁷,Bisson Gregory P³⁸

Affiliation:

1. School of Medicine and Rollins School of Public Health, Emory University, Atlanta, Georgia

2. Aurum Institute, Johannesburg, South Africa

3. Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia

4. Nuclear Medicine, CM Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

5. Advancing Care and Treatment for TB/HIV, a Collaborating Centre of the South African Medical Research Council, Johannesburg, South Africa

6. School of Public Health, University of the Witwatersrand, Johannesburg, South Africa

7. Department of Medicine, University of Massachusetts Medical School, Worcester

8. Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia

Abstract

Abstract End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.

Funder

National Institute of Allergy and Infectious Diseases

National Center for Advancing Translational Sciences

Emory University and University of Pennsylvania Centers for AIDS Research

Advancing Care and Treatment for TB/HIV

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/article-pdf/70/8/1750/33031840/ciz733.pdf

Reference15 articles.