Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet

Author:

Loche Elena1,Blackmore Heather L1,Carpenter Asha A1,Beeson Jessica H1,Pinnock Adele1,Ashmore Thomas J1,Aiken Catherine E12,de Almeida-Faria Juliana13,Schoonejans Josca M1,Giussani Dino A4,Fernandez-Twinn Denise S1,Ozanne Susan E1

Affiliation:

1. University of Cambridge Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Wellcome Trust-MRC Institute of Metabolic Science, Level 4, Box 289, Addenbrookes' Treatment Centre, Addenbrookes' Hospital, Hills Road, Cambridge, CB2 OQQ, UK

2. Department of Obstetrics and Gynaecology, The Rosie Hospital and NIHR Cambridge Comprehensive Biomedical Research Centre, University of Cambridge, Box 223, Cambridge, CB2 0SW, UK

3. University of Campinas, Faculty of Medical Sciences, Obesity and Comorbidities Research Center, Campinas, 13083-864, Brazil

4. Department of Physiology, Development & Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK

Funder

Medical Research Council

British Heart Foundation

São Paulo Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference58 articles.

1. Body fatness and cancer–viewpoint of the IARC Working Group;Lauby-Secretan;N Engl J Med,2016

2. Cardiovascular disease in Europe: epidemiological update 2016;Townsend;Eur H J,2016

3. Preconceptional and maternal obesity: epidemiology and health consequences;Poston;Lancet Diabetes Endocrinol,2016

4. Maternal obesity: lifelong metabolic outcomes for offspring from poor developmental trajectories during the perinatal period;Zambrano;Arch Med Res,2016

5. Effect of in utero and early-life conditions on adult health and disease;Gluckman;N Engl J Med,2008

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