The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures-Reference-Cited by-同舟云学术

The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures

Published:2019-11-14 Issue:D1 Volume:48 Page:D376-D382
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Andreeva Antonina¹,Kulesha Eugene²,Gough Julian¹,Murzin Alexey G¹

Affiliation:

1. MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK

2. EKMM Limited, Cambridge CB1 9AZ, UK

Abstract

Abstract The Structural Classification of Proteins (SCOP) database is a classification of protein domains organised according to their evolutionary and structural relationships. We report a major effort to increase the coverage of structural data, aiming to provide classification of almost all domain superfamilies with representatives in the PDB. We have also improved the database schema, provided a new API and modernised the web interface. This is by far the most significant update in coverage since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. The database is accessible from http://scop.mrc-lmb.cam.ac.uk.

Funder

Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/48/D1/D376/33024560/gkz1064.pdf

Reference23 articles.

1. SCOP: a structural classification of proteins database for the investigation of sequences and structures;Murzin;J. Mol. Biol.,1995

2. SCOP2 prototype: a new approach to protein structure mining;Andreeva;Nucleic Acids Res.,2014

3. SIFTS: updated Structure Integration with Function, Taxonomy and Sequences resource allows 40-fold increase in coverage of structure-based annotations for proteins;Dana;Nucleic Acids Res.,2019