Optimization of Isocratic Ion Chromatography Methods for Simultaneous Inorganic Anions and Carboxylic Acids Determination

Abstract

As a part of preliminary studies, the possibility of quantitative oxidation of aldehydes to carboxylic acids and their determination by isocratic ion chromatography with conductometric detection has been tested. A methodology for the simultaneous separation of inorganic anions (F-, Cl-, NO2-, Br-, NO3-, PO43-, SO42-) and carboxylic acids (formate, acetate and oxalate) by using isocratic ion chromatography with conductivity detection have been developed and validated. Six anion-exchange columns were tested. The best results were achieved for Dionex IonPac AS10 column with 50mM NaOH eluent and flow rate of 1.0 mL∙min-1.