Affiliation:
1. Delta State University of Science and Technology
2. Novena University
Abstract
Consumption of cassava meal affected by crude oil has significant effects on lipid and protein metabolism. The hepatoprotective action of spices is mostly attributed to the suppression of lipid oxidation and protein breakdown. This study examined the protein restoration and anti-lipidemic potential of Monodora myristica (Gaertn.) in rats fed with cassava contaminated with crude oil.
The research involved 36 albino rats separated into six groups (n = 6). Group 1 (control) consumed cassava without crude oil. Group 2 received cassava with crude oil. Groups 3, 4, and 5 fed on cassava with crude oil and various extracts of M. myristica, i.e., aqueous, ethanol, and diethyl ether, respectively. Group 6 received non-ionic synthetic surfactant Tween 80. The experiment relied on standard methods.
Blood serum and liver obtained from the rats of Group 2 showed a significant (p < 0.05) increase in total cholesterol, low density lipoprotein cholesterol, triacylglycerol, and malondialdehyde, as well as a decrease in total protein, albumin, and high-density lipoprotein cholesterol. The groups that received M. myristica extracts showed a significant increase (p < 0.05) in total protein, albumin, and high-density lipoprotein cholesterol. They also had lower total cholesterol, low density lipoprotein cholesterol, triacylglycerol, and malondialdehyde as compared to Group 2, which dieted on cassava contaminated with crude oil without additives.
In this research, crude oil-contaminated cassava affected proteins and lipids in rats. Diethyl ether extract of M. myristica demonstrated the best anti-lipidemic and protein restoration.
Publisher
Kemerovo State University
Subject
Food Science,Agricultural and Biological Sciences (miscellaneous),General Veterinary
Reference25 articles.
1. Adeniyi VA, Akangbe JA, Kolawole AE, Ayeni MD, Olorunfemi DO. Women cassava processors’ livelihood; implications for improved processing technology usage in Nigeria. Cogent Social Sciences. 2023;9(1). https://doi.org/10.1080/23311886.2023.2191898, Adeniyi VA, Akangbe JA, Kolawole AE, Ayeni MD, Olorunfemi DO. Women cassava processors’ livelihood; implications for improved processing technology usage in Nigeria. Cogent Social Sciences. 2023;9(1). https://doi.org/10.1080/23311886.2023.2191898
2. Anyaegbu CN, Okpara KE, Taweepreda W, Akeju D, Techato K, Onyeneke RU, et al. Impact of climate change on cassava yield in Nigeria: An autoregressive distributed lag bound approach. Agriculture. 2023;13(1). https://doi.org/10.3390/agriculture13010080, Anyaegbu CN, Okpara KE, Taweepreda W, Akeju D, Techato K, Onyeneke RU, et al. Impact of climate change on cassava yield in Nigeria: An autoregressive distributed lag bound approach. Agriculture. 2023;13(1). https://doi.org/10.3390/agriculture13010080
3. Onuoha SC, Chukwuma CC. Biochemical investigations of Albino rats orally exposed to Bonny light crude oil and leaf extract of Cnidoscolus aconitifolius. International Journal of Biological Studies. 2023;3(1):1–16. https://doi.org/10.47941/ijbs.1183, Onuoha SC, Chukwuma CC. Biochemical investigations of Albino rats orally exposed to Bonny light crude oil and leaf extract of Cnidoscolus aconitifolius. International Journal of Biological Studies. 2023;3(1):1–16. https://doi.org/10.47941/ijbs.1183
4. Udousoro LL, Ebiekpi IE, Otong EJ. Proximate compositions anti-nutrients and heavy metals contents in edible leafy vegetables in Akwa Ibom State, Nigeria. Book of Abstracts, 2nd World Conference on Applied Science and Technology; 2018., Udousoro LL, Ebiekpi IE, Otong EJ. Proximate compositions anti-nutrients and heavy metals contents in edible leafy vegetables in Akwa Ibom State, Nigeria. Book of Abstracts, 2nd World Conference on Applied Science and Technology; 2018.
5. Melebary SJ, Elnaggar MHR. Impact of Moringa oleifera leaf extract in reducing the effect of lead acetate toxicity in mice. Saudi Journal of Biological Sciences. 2023;30(1). https://doi.org/10.1016/j.sjbs.2022.103507, Melebary SJ, Elnaggar MHR. Impact of Moringa oleifera leaf extract in reducing the effect of lead acetate toxicity in mice. Saudi Journal of Biological Sciences. 2023;30(1). https://doi.org/10.1016/j.sjbs.2022.103507