The relationship between inflammatory markers and mortality in patients undergoing proximal femoral nail fixation for intertrochanteric femur fractures

Abstract

Aim: This study aimed to investigate the predictability of mortality based on biomarkers measured using complete blood count in geriatric patients who underwent proximal femoral nail fixation for intertrochanteric femur fractures. Methods: We included in this retrospective study 247 patients who had undergone proximal femoral nailing due to osteoporotic intertrochanteric femur fracture. The patients were divided into two groups according to 1-year mortality outcome: group A, survivors (n=162), and group B, deceased patients (n=85). Preoperative demographic information, the number of days until surgery, C-reactive protein (CRP) level, hemoglobin level, platelet-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and systemic immune-inflammatory index (SII) were recorded. Results: No statistically significant differences were found between the groups in terms of sex, type of anesthesia, leukocyte count, and neutrophil level (p>0.05), but statistically significant differences were found in age, number of days until surgery, CRP level, hemoglobin level, lymphocyte count, and platelet count (p