Abstract
Aims and Objectives: This study aimed to assess and compare follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, and thyroid-stimulating hormone (TSH) levels in normal fertile females, patients with primary infertility, and patients with early pregnancy loss (EPL).
Methods: Patients were divided into three groups of 25 each. Group I consisted of patients of primary infertility, Group II consisted of patients of EPL, and Group C consisted of normal fertile females and acted as the control group. Hormone levels in different groups were compared statistically.
Results: FSH levels in the infertility group (Group I) and control group (Group C) were similar (p>0.05). The difference between the FSH levels of EPL (Group II) and the control group (Group C) was statistically significant (p<0.05). There was a statistically significant difference between LH levels of the infertility group (Group I), EPL (Group II), and control group (Group C) (p<0.05). The difference between prolactin levels of the infertility group (Group I), EPL (Group II), and control group (Group C) was also statistically significant (p<0.05). The difference between the TSH levels of the infertility group (Group I), EPL (Group II), and control group (Group C) was also statistically significant (p<0.05).
Conclusion: This study supports the fact that women with infertility and repeated abortions have altered hypothalamic–pituitary–ovarian axis as compared to fertile women.
Publisher
Innovare Academic Sciences Pvt Ltd
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology