ASSESSMENT OF TOTAL INTRAVENOUS ANAESTHESIA BY PROPOFOL AND INHALATIONAL ANAESTHESIA WITH ISOFLURANE FOR CONTROLLED HYPOTENSION IN FUNCTIONAL ENDOSCOPIC SINUS SURGERY

Abstract

Objective: The key objective of the study is to compare the Propofol-based total intravenous anaesthesia (TIVA) with Isoflurane-based inhalational anaesthesia for controlled hypotension during functional endoscopic sinus surgery (FESS). Materials and Methods: This is a prospective randomized, controlled single-blinded clinical study. The study involved 40 patients posted for elective FESS surgery, selected randomly from the ENT department. Anesthesia was induced with Inj. Midazolam 2 mg, Inj. Fentanyl 2 µg/kg, Inj. Propofol 2 mg/kg, Inj. Vecuronium 0.1 mg /kg and ventilated using oxygen, air, and Isoflurane (FiO2 of 0.5) in isofurane group  patients. Injections of 2 mg of midazolam, 2 µg/kg of fentanyl, 2 mg/kg propofol, and 0.1 mg /kg vecuronium, as well as oxygen and air for ventilation, were used to induce anaesthesia (FIO2 of 0.5) in TIVA group patients. Fromme boezaart scale was used as an evaluation scale for surgical site bleeding. Results: The average blood loss in the isoflurane group was 134.25 ± 4.65ml and in the propofol group was 66.95 ± 4.28ml. The quality of the surgical field in the propofol group is (3.13 ± 0.9), and the isoflurane group is (3.13 ± 0.8). The results are significant. Conclusion: Total intravenous anesthesia using propofol provides notable advantages over the traditionally used inhalational anesthetic technique using isoflurane in surgical field conditions and intraoperative blood loss.