A NEW GROWTH FACTOR REQUIRED BY CERTAIN HEMOLYTIC STREPTOCOCCI

Author:

Woolley D. W.1

Affiliation:

1. From the Laboratories of The Rockefeller Institute for Medical Research

Abstract

A new factor essential for the growth of hemolytic streptococci of Lancefield's group A has been demonstrated. It has not been possible to identify this factor with any other known growth factor. The active substance occurred in liver as a water-soluble, alcohol-insoluble, non-dialyzable material. It could be rendered dialyzable by treatment in strong alcohol with HCl, but not by many less drastic procedures. The most active concentrates prepared gave a maximal effect when approximately 10 gamma per cc. were added.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

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