Management Protocol for Abacavir-Related Hypersensitivity Reaction-Reference-Cited by-同舟云学术

Management Protocol for Abacavir-Related Hypersensitivity Reaction

Published:2000-02 Issue:2 Volume:34 Page:247-249
ISSN:1060-0280
Container-title:Annals of Pharmacotherapy
language:en
Short-container-title:Ann Pharmacother

Author:

Clay Patrick G¹,Rathbun R Chris²,Slater Leonard N³

Affiliation:

1. Patrick G Clay PharmD, at time of writing, Fellow of Infectious Diseases, College of Pharmacy, University of Oklahoma, Oklahoma City, OK; now, HIV Clinical Specialist, Assistant Professor, Division of Pharmacy Practice, University of Missouri-Kansas City, Kansas City, MO

2. R Chris Rathbun PharmD, Associate Professor, Department of Pharmacy Practice, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City

3. Leonard N Slater MD, Professor of Medicine, Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center

Abstract

OBJECTIVE: To develop an abacavir hypersensitivity reaction management protocol for the University of Oklahoma Health Sciences Center. DATA SYNTHESIS: Conference abstracts, published literature, and manufacturer-provided materials were reviewed to define the syndrome and manifestations and to recommend steps to take when a patient develops abacavir-related reactions. RESULTS: Initial education, formalized contact and response mechanism, and intervention levels were incorporated into a protocol for clinicians. CONCLUSIONS: Abacavir, a newly approved agent for the treatment of HIV, has been associated with a fatal hypersensitivity reaction. Our protocol provides a mechanism to minimize progression of abacavir hypersensitivity reaction by providing a formalized management procedure

Publisher

SAGE Publications

Subject

Pharmacology (medical)

Link

http://journals.sagepub.com/doi/pdf/10.1345/aph.19107

Reference13 articles.

1. Potential confusion with antiretroviral drugs

2. Two antiretroviral drugs likely to be confused

3. How Many Pills Do Patients With HIV Infection Take?

4. McEvoy GK, ed. American Hospital Formulary Service drug information 1998. Bethesda, MD: American Society of Health System Pharmacists, 1998: 560–2.

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. HLA-B*57:01 screening and hypersensitivity reaction to abacavir between 1999 and 2016 in the OPERA® observational database: a cohort study;AIDS Research and Therapy;2019-01-16

2. Engaging Pharmacy Students, Residents, and Fellows in Antimicrobial Stewardship;Journal of Pharmacy Practice;2014-01-07

3. T Cell Responses to Drugs and Drug Metabolites;T Lymphocytes as Tools in Diagnostics and Immunotoxicology;2013-10-23

4. Systemic antiviral agents;Comprehensive Dermatologic Drug Therapy;2013

5. HIV/AIDS;Braun-Falco’s Dermatology;2009