Affiliation:
1. From Memorial Sloan-Kettering Cancer Center, New York, NY. Dr Dhall is currently with the Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, Calif
Abstract
Abstract
Nested variant of urothelial carcinoma is a rare neoplasm that is histologically characterized by large numbers of small, closely packed, haphazardly arranged, poorly defined, confluent irregular nests of bland-appearing urothelial cells infiltrating the lamina propria and the muscularis propria. Due to the cells' deceptively bland appearance, the tumors are sometimes misdiagnosed as benign lesions, leading in some cases to a significant delay in establishing the correct diagnosis and thus contributing to this neoplasm's advanced stage. Nested variant of urothelial carcinoma must be differentiated from the benign proliferative lesions of urothelium, such as von Brunn nests, cystitis cystica, cystitis glandularis, nephrogenic adenoma, inverted papilloma, and paraganglioma.
Publisher
Archives of Pathology and Laboratory Medicine
Reference14 articles.
1. The nested variant of transitional cell carcinoma– a rare neoplasm with poor prognosis.;Holmang;Scand J Urol Nephrol,2001
2. Unusual benign bladder tumor of Brunn nest origin.;Stern;Urology,1979
3. Carcinomas of the urinary bladder with deceptively benign-appearing foci: a report of three cases.;Talbert;Am J Surg Pathol,1989
4. The nested variant of transitional cell carcinoma: a neoplasm resembling proliferation of Brunn's nests.;Murphy;Mod Pathol,1992
5. The nested variant of transitional cell carcinoma: an aggressive neoplasm with innocuous histology.;Drew;Mod Pathol,1996
Cited by
52 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献