Evaluation of the effectiveness of combined treatment in patients with comorbid COPD and GERD

Abstract

Gastroesophageal reflux disease (GERD) is often comorbid with chronic obstructive pulmonary disease (COPD). Such coexisting pathology in the initial stage, which is present in young patients, but poorly studied. The purpose of our study is to study the effectiveness of the use of combined therapy using the example of the addition of Dalargin in patients with GERD and COPD. We took into the study 60 young people with a confirmed combined course of GERD and COPD and divided them into two equal groups. The first group received an addition to the basic treatment Dalargin, and the second group — placebo. The effectiveness of the treatment was evaluated by comparing the indicators of ERF, gastric juice pH, norepinephrine level, and depressive and anxiety disorders. It was established that combined treatment in patients with GERD with concomitant COPD reliably improves all the studied indicators.