Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists

Author:

Rybak Michael J.123,Lomaestro Ben M.4,Rotscahfer John C.5,Moellering Robert C.678,Craig Willam A.9,Billeter Marianne10,Dalovisio Joseph R.11,Levine Donald P.3

Affiliation:

1. Anti-Infective Research Laboratory, Department of Pharmacy Practice, College of Pharmacy & Health Sciences, and Detroit Receiving Hospital & University Health Center, Detroit, Michigan

2. Department of Medicine, School of Medicine, Wayne State University, and Detroit Receiving Hospital & University Health Center, Detroit, Michigan

3. Detroit Receiving Hospital & University Health Center, Detroit, Michigan

4. Albany Medical Center, Albany, New York

5. Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis

6. Shields Warren-Mallinckrodt Medical Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

7. Harvard Medical School, and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

8. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

9. University of Wisconsin School of Medicine and Public Health, Madison

10. Oshsner Medical Centers and Department of Infectious Diseases, Oschsner Health System, New Orleans, Louisiana

11. Department of Infectious Diseases, Oschsner Health System, New Orleans, Louisiana

Abstract

Abstract Practice guidelines for therapeutic monitoring of vancomycin treatment for Staphylococcus aureus infection in adult patients were reviewed by an expert panel of the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists. A literature review of existing evidence regarding vancomycin dosing and monitoring of serum concentrations, in addition to patient outcomes combined with expert opinion regarding the drug's pharmacokinetic, pharmacodynamic, and safety record, resulted in new recommendations for targeting and adjustment of vancomycin therapy.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference2 articles.

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