The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism
Author:
Affiliation:
1. Wenzhou Medical University, Wenzhou, China
2. Shaoxing People’s Hospital, Shaoxing, China
3. The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Abstract
Funder
National Key Research and Development Program of China
National Natural Science Foundation of China
Natural Science Foundation of Zhejiang Province
Wenzhou Municipal Science and Technology Bureau
Publisher
PeerJ
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://peerj.com/articles/16601.pdf
Reference37 articles.
1. EGFR TKI combination with immunotherapy in non-small cell lung cancer;Ahn;Expert Opinion on Drug Safety,2017
2. Onco-cardiology: drug-drug interactions of antineoplastic and cardiovascular drugs;Akbulut;Critical Reviews in Oncology/Hematology,2020
3. Evaluation of the effects of apatinib on the pharmacokinetics of venlafaxine and O-desmethylvenlafaxine in SD male rats by UPLC-MS/MS;Bao;Basic & Clinical Pharmacology & Toxicology,2018
4. Evaluation of recombinant CYP3A4 variants on the metabolism of oxycodone in vitro;Cai;Chemical Research in Toxicology,2021
5. Relative contributions of the major human CYP450 to the metabolism of icotinib and its implication in prediction of drug-drug interaction between icotinib and CYP3A4 inhibitors/inducers using physiologically based pharmacokinetic modeling;Chen;Expert Opinion on Drug Metabolism & Toxicology,2015
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3