Abstract
The spread of cancer is one of the biggest obstacles at the present time, which has caused panic to people on the health and psychological level, adding to the economic burdens and human losses at the level of most countries of the world. For this reason, most medical institutions and researchers have shown great interest in this field to find the appropriate way out by finding sincere treatments for this problem.The current study includes a review of the immuno-histological role of the CD133 indicator in the development and severity of stomach cancer in order to be a key for applied studies to employ this indicator in the diagnosis or treatment of gastric cancer.