Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis

Author:

Hou Yi-Chou12,Liao Min-Tser34,Tsai Kuo-Wang5,Zheng Cai-Mei67,Chiu Hui-Wen789,Lu Kuo-Cheng21011

Affiliation:

1. Division of Nephrology, Department of Internal Medicine, Cardinal Tien Hospital, New Taipei City, Taiwan

2. School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan

3. Department of Pediatrics, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan

4. Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan

5. Department of Medical Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan

6. Department of Internal Medicine, Division of Nephrology, Shuang Ho Hospital, School of Medicine, College of Medicine, Taipei Medical University, New Taipei City 11031, Taiwan

7. TMU Research Centre of Urology and Kidney, Taipei Medical University, New Taipei City 11031, Taiwan

8. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, New Taipei City 11031, Taiwan

9. Department of Medical Research, Shuang Ho Hospital, Taipei Medical University, New Taipei City 11031, Taiwan

10. Division of Nephrology, Department of Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan

11. Division of Nephrology, Department of Medicine, Fu Jen Catholic University Hospital, School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

Reference42 articles.

1. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.;National Kidney Foundation;Am J Kidney Dis,2002

2. The KDOQI 2002 classification of chronic kidney disease: for whom the bell tolls.;Orth;Nephrol Dial Transplant,2010

3. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO).;Eknoyan;Kidney Int,2005

4. The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: a systematic review.;Glorieux;J Am Soc Nephrol,2014

5. Impacts of Indoxyl Sulfate and p-Cresol Sulfate on Chronic Kidney Disease and Mitigating Effects of AST-120.;Lu;Toxins (Basel),2018

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