Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL

Author:

Li Bin123,Zhang Guangsen2,Li Cui1,Li Ruijuan2,Lu Jingchen3,He Zhengxi3,Wang Quan3,Peng Zhenzi1,Wang Jun1,Dong Yeping1,Zhang Chunfang1,Tan Jie Qiong4,Bahri Nacef5,Wang Yuexiang56,Duan Chaojun1

Affiliation:

1. Medical Research Center, Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, People’s Republic of China

2. Division of Hematology, Institute of Molecular Hematology, The Second Xiang Ya Hospital, Central South University, Changsha, People’s Republic of China

3. Division of Oncology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China

4. State Key Laboratory of Medical Genetics, Xiangya Medical School, Central South University, Changsha, People’s Republic of China

5. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA

6. The Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences/Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China

Publisher

Impact Journals, LLC

Subject

Oncology

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