Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

Author:

Liu Ningning12,Li Xiaofen1,Huang Hongbiao1,Zhao Chong1,Liao Siyan1,Yang Changshan1,Liu Shouting1,Song Wenbin1,Lu Xiaoyu1,Lan Xiaoying1,Chen Xin1,Yi Songgang1,Xu Li13,Jiang Lili1,Zhao Canguo1,Dong Xiaoxian1,Zhou Ping1,Li Shujue14,Wang Shunqing1,Shi Xianping1,Dou Ping Q.15,Wang Xuejun16,Liu Jinbao1

Affiliation:

1. State Key Lab of Respiratory Disease, Protein Modification and Degradation Lab, Department of Pathophysiology, Guangzhou Medical University, Guangdong, China

2. Guangzhou Research Institute of Cardiovascular Disease, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China

3. Department of Hematology, The People's Hospital of Guangxi Autonomous Region, Nanning, Guangxi, People's Republic of China

4. Guangzhou Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China

5. The Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, and Departments of Oncology, Pharmacology and Pathology, School of Medicine, Wayne State University, Detroit, Michigan, USA

6. Division of Basic Biomedical Sciences, Sanford School of Medicine of the University of South Dakota, Vermillion, South Dakota, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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