The changing 50% inhibitory concentration (IC50) of cisplatin: a pilot study on the artifacts of the MTT assay and the precise measurement of density-dependent chemoresistance in ovarian cancer

Author:

He Yifeng123,Zhu Qiujing124,Chen Mo5,Huang Qihong3,Wang Wenjing124,Li Qing124,Huang Yuting6,Di Wen124

Affiliation:

1. Department of Obstetrics and Gynecology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China

2. Shanghai Key Laboratory of Gynecologic Oncology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China

3. Tumor Microenvironment and Metastasis Program, The Wistar Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

4. State Key Laboratory of Oncogene and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China

5. Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China

6. Children's Research Institute, Children's National Medical Center, Washington DC 20010, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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