Assessing the Brighton Collaboration Case Definition of Sensorineural Hearing Loss in Ghana

Author:

Bukari Iddrisu1,Huang Wan-Ting12,Issahalq Duah Mohammed3,Agyemang-Prempeh Akosua A.3,Konney Anna3,Yussif Hamidu4,Yakubu Yakubu A.5,Geisler Christopher Hammond6,Chen Wei J.78

Affiliation:

1. Global Health Program, College of Public Health, National Taiwan University, Taipei, Taiwan;

2. National Taiwan University Children’s Hospital, Taipei, Taiwan;

3. Eye, Ear, Nose and Throat Department, Komfo Anokye Teaching Hospital, Kumasi, Ghana;

4. Public Health Department, Komfo Anokye Teaching Hospital, Kumasi, Ghana;

5. Graduate Centre of Management, Cape Peninsula University of Technology, Cape Town, South Africa;

6. Pantang Hospital, Ghana Health Service, Accra, Ghana;

7. Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan;

8. Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan

Abstract

ABSTRACT. The Brighton Collaboration has developed a case definition to assess sensorineural hearing loss (SNHL) as an adverse event of special interest for Lassa fever vaccines. We applied the level of diagnostic certainty (LOC) criteria to 300 SNHL patients aged 18 to 59 years at a tertiary hospital in Ghana from January 2017 through June 2020 and evaluated the applicability of this definition. Most SNHL cases were assessable (85.0%) and assigned level 1 LOC (84.3%); missing information on otoscopy (86.7%) was the main reason for being unable to classify cases. Consistency of LOC classification between assessors was 99.3%. Cases with electronic medical records (EMRs) were less assessable than those with paper records (30.9% versus 93.8%). These findings indicate that the SNHL definition would be applicable to retrospectively ascertain and classify cases in resource-limited settings. Developing an EMR template to document otoscopy results may improve the feasibility at this hospital to ascertain SNHL.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference19 articles.

1. Management of patients with suspected viral hemorrhagic fever,1998

2. Lassa fever-induced sensorineural hearing loss: a neglected public health and social burden;Mateer,2018

3. A review of Lassa fever vaccine candidates;Salami,2019

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