Seasonal and Temporal Trends of Infectious Keratitis in Northern Vietnam

Author:

Cao Binh1,Vu Chi Hoang Viet2,Le Cung Xuan2,Hoang Anh Tuan2,Pham Ngoc Dong2,Nguyen Xuan Hiep2,Whitcher John P.13,Keenan Jeremy D.13

Affiliation:

1. Francis I Proctor Foundation, University of California, San Francisco, California;

2. Vietnam National Eye Hospital, Hanoi, Vietnam;

3. Department of Ophthalmology, University of California, San Francisco, California

Abstract

ABSTRACT. The epidemiology of corneal ulcers in Vietnam has not been well characterized. In this report, we reviewed retrospectively the microbiological data of patients with a clinical diagnosis of corneal ulcer at the microbiology laboratory of Vietnam National Eye Hospital from January 1, 2010 to March 31, 2023. We observed a seasonal pattern for fungal and microsporidial keratitis, with an annual peak in November, and an inverse relationship between fungal keratitis and inclement weather. The November peak coincided with one of the major harvesting seasons in Vietnam. We also observed increasing numbers of microsporidial and Acanthamoeba keratitis cases in recent years. Knowledge of these trends are helpful in guiding empirical treatment of corneal infections and preventing corneal blindness.

Publisher

American Society of Tropical Medicine and Hygiene

Subject

Virology,Infectious Diseases,Parasitology

Reference18 articles.

1. Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis;Flaxman,2017

2. Incidence of corneal ulceration in Madurai District, South India;Gonzales,1996

3. Incidence of ulcerative keratitis in a defined population from 1950 through 1988;Erie,1993

4. Empirical assessment of alternative methods for identifying seasonality in observational healthcare data;Molinaro,2022

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