A Study on the Progress of Astragalus-Coptis Chinensis Medicinal Pair in the Treatment of Diabetes Mellitus

Abstract

According to the relevant studies in recent years, it was found that astragalus - Coptis Chinensis drug pair and its analogous formula have a broad prospect for the treatment of type 2 diabetes mellitus (T2DM). Pharmacological studies have shown that Coptis Chinensis possesses the pharmacological activities of antimicrobial, anti-inflammatory, anti-tumor, lipid regulating, hypoglycemic, anti-arrhythmic, and antioxidant activities[1], and Astragalus possesses the effects of enhancing the function of the immune system, antimyocardial ischemia, bi-directional regulation of blood pressure, anti-tumor, anti-aging, hypoglycemia, and protection of metabolic tissues (liver and kidneys, etc.) [2] [3], the use of Astragalus and Coptis Chinensis pairs has demonstrated significant multiple effects. Specifically, this combination not only effectively reduces blood glucose levels, but also significantly enhances the body's sensitivity to insulin, thus helping to improve the phenomenon of insulin resistance and further enhance the overall health status of patients [1][2][3]. This paper analyzes and researches the research progress of astragalus-Coptis Chinensis medicinal pair and its analogous formulae in the treatment of type 2 diabetes mellitus and the improvement of its complications through the collation and summarization of the literature, in order to lay a certain theoretical research foundation for the clinical diagnosis and treatment of type 2 diabetes mellitus by astragalus-Coptis Chinensis medicinal pair and its related formulae, prevention of diabetes mellitus complications, and rational use of medicines in diabetes mellitus clinical treatment.