Specific down‐regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
Author:
Affiliation:
1. Department of PharmacologyKalypsys Inc.San DiegoCaliforniaUSA
2. Department of DiabetesBeckman Research Institute of City of HopeDuarteCaliforniaUSA
3. Department of Pfizer Inc.St. LouisMissouriUSA
Funder
National Institutes of Health
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.06-6713com
Reference41 articles.
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3. Transforming growth factor beta contributes to progressive diabetic nephropathy
4. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.
5. High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta;Han D. C.;J.Am. Soc. Nephrol.,1999
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