Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

Author:

Poole Kenneth E. S.1,Van Bezooijen Rutger L.23,Loveridge Nigel1,Hamersma Herman4,Papapoulos Socrates E.2,Löwik Clemens W.2,Reeve Jonathan1

Affiliation:

1. Bone Research GroupDepartment of MedicineUniversity of CambridgeAddenbrooke's Hospital Cambridge United Kingdom

2. Department of Endocrinology and Metabolic DiseasesLeiden University Medical Centre Leiden Netherlands

3. Department of Molecular Cell BiologyLeiden University Medical Centre Leiden Netherlands

4. South Africa

Funder

Medical Research Council

National Osteoporosis Society

European Commission

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference35 articles.

1. The osteocyte

2. A quantitative evaluation of osteoblast-osteocyte relationships on growing endosteal surface of rabbit tibiae

3. The structure of bone tissues and the cellular control of their deposition;Marotti G.;Ital. J. Anat. Embryol.,1996

4. Does osteocyte formation cause the nonlinear refilling of osteons?

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