Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide‐derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling

Author:

Brook Matthew S.1,Wilkinson Daniel J.1,Mitchell William K.12,Lund Jonathan N.12,Szewczyk Nathaniel J.1,Greenhaff Paul L.1,Smith Ken1,Atherton Philip J.1

Affiliation:

1. Medical Research Council‐Arthritis Research UK Centre of Excellence for Musculoskeletal Ageing ResearchDivision of Clinical, Metabolic, and Molecular PhysiologyUniversity of NottinghamDerbyUnited Kingdom

2. Department of SurgeryRoyal Derby HospitalDerbyUnited Kingdom

Funder

Dunhill Medical Trust

University of Nottingham

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference70 articles.

1. Mechanism of work‐induced hypertrophy of skeletal muscle;Goldberg A. L.;Med. Sci. Sports,1975

2. Health benefits of physical activity: the evidence

3. Changes in RNA, DNA and protein content and the rates of protein synthesis and degradation during hypertrophy of the anterior latissimus dorsi muscle of the adult fowl (Gallus domesticus);Laurent G. J.;Growth,1977

4. Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men

5. Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise

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