Prophylactic Prednisolone Promotes AAV5 Hepatocyte Transduction Through the Novel Mechanism of AAV5 Coreceptor Platelet-Derived Growth Factor Receptor Alpha Upregulation and Innate Immune Suppression
Author:
Affiliation:
1. Biology Research; BioMarin Pharmaceutical, Inc.; Novato, California, USA.
2. Global Clinical Sciences; BioMarin Pharmaceutical, Inc.; Novato, California, USA.
3. Translational Sciences; BioMarin Pharmaceutical, Inc.; Novato, California, USA.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
https://www.liebertpub.com/doi/pdf/10.1089/hum.2023.065
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4. Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B
5. Overcoming innate immune barriers that impede AAV gene therapy vectors
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