Predictive Value of ABCC2 and UGT1A1 Polymorphisms on Irinotecan-Related Toxicities in Patients with Cancer

Author:

Aoullay Zineb123ORCID,Smith Andrew2,Slaoui Meriem4,El Bouchikhi Ihssane56,Ghazal Hassan78,Al Idrissi Najib9,Meddah Bouchra1,Lynch Kara L.2,Cherrah Yahia1,Wu Alan H.B.2

Affiliation:

1. Department of Sciences du Médicament, Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy of Rabat, University Mohamed V Rabat, Rabat, Morocco.

2. Department of Laboratory Medicine, University of California San Francisco and Zuckerberg San Francisco General Hospital, San Francisco, California, USA.

3. Institut de Recherche sur le Cancer-IRC, Fes, Morocco.

4. Research Team in Tumour Pathology, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.

5. Medical Genetics and Oncogenetics Laboratory, Hassan II University Hospital, Fez, Morocco.

6. Multidisciplanary Laboratory for Research & Innovation, GBG Department, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University, Khouribga, Morocco.

7. Department of Fundamental Sciences, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, Morocco.

8. National Center for Scientific and Technical Research, Rabat, Morocco.

9. Department of Surgery, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, Morocco.

Publisher

Mary Ann Liebert Inc

Subject

Genetics (clinical),General Medicine

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