Influence of TPMT and NUDT15 Genetic Polymorphisms on Mercaptopurine Pharmacokinetics in Healthy Volunteers-Reference-Cited by-同舟云学术

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Influence of TPMT and NUDT15 Genetic Polymorphisms on Mercaptopurine Pharmacokinetics in Healthy Volunteers

Published:2024-08-01 Issue:8 Volume:28 Page:322-327
ISSN:1945-0265
Container-title:Genetic Testing and Molecular Biomarkers
language:en
Short-container-title:Genetic Testing and Molecular Biomarkers

Author:

Kong Qihui¹,Zhang Qiqi²,Chen Di²,Lou Jinfang³,Zhu Jian⁴,Chen Mingjing²,Li Ting²^ORCID

Affiliation:

1. School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China.

2. The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou, China.

3. Hangzhou Bio-Sincerity Pharma-Tech Co., Ltd, Hangzhou, China.

4. Zhejiang Aotuokang Pharmaceutical Group Inc. Co., Jinhua, Zhejiang, China.

Publisher

Mary Ann Liebert Inc

Link

https://www.liebertpub.com/doi/pdf/10.1089/gtmb.2023.0605

Reference18 articles.

1. NUDT15 C415T variant compared with TPMT genotyping in predicting azathioprine‐induced leucopenia: prospective analysis of 1014 inflammatory bowel disease patients in India

2. 6-mercaptopurine promotes energetic failure in proliferating T cells

3. Thiopurine Drugs in the Treatment of Ulcerative Colitis: Identification of a Novel Deleterious Mutation in TPMT

4. Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis

5. Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping

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