Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill <i>NQO1</i>-Positive Pancreatic Cancer Cells-Reference-Cited by-同舟云学术

Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1-Positive Pancreatic Cancer Cells

Published:2024-01-08 Issue: Volume: Page:
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Jiang Lingxiang¹,Liu Yingchun¹²,Tumbath Soumya¹,Boudreau Matthew W.³⁴,Chatkewitz Lindsay E.³⁴,Wang Jiangwei¹,Su Xiaolin⁵,Zahid Kashif Rafiq¹,Li Katherine¹,Chen Yaomin⁶,Yang Kai⁷⁸,Hergenrother Paul J.³⁴⁹,Huang Xiumei¹^ORCID

Affiliation:

1. Department of Radiation Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.

2. Laboratory of Stem Cell Engineering and Regenerative Medicine, Fujian Province University/School of Basic Medical Sciences, Fujian Medical University, Fuzhou, P.R. China.

3. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

4. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

5. Department of Biochemistry and Molecular Biology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.

6. Indiana University Health Pathology Laboratory, Indiana University School of Medicine, Indianapolis, Indiana, USA.

7. Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA.

8. The Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.

9. Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/ars.2022.0224

Reference75 articles.

1. Inhibition of retinoic acid receptor β signaling confers glycolytic dependence and sensitization to dichloroacetate in melanoma cells

2. Mitochondrial and Nuclear Cross Talk in Cell Death

3. Glutathione in Cellular Redox Homeostasis: Association with the Excitatory Amino Acid Carrier 1 (EAAC1)

4. N-Acetylcysteine—a safe antidote for cysteine/glutathione deficiency

5. NQO1 Expression in Pancreatic Cancer and Its Potential Use as a Biomarker