The Use of High-Content Screening for the Discovery and Characterization of Compounds That Modulate Mitotic Index and Cell Cycle Progression by Differing Mechanisms of Action
Author:
Affiliation:
1. Serenex, Inc., Durham, NC.
2. Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2006.4.153
Reference19 articles.
1. High-Content Screening Assay for Activators of the Wnt/Fzd Pathway in Primary Human Cells
2. A Quantitative Cell-Based High-Content Screening Assay for the Epidermal Growth Factor Receptor-Specific Activation of Mitogen-Activated Protein Kinase
3. A Quantitative High-Throughput Endothelial Cell Migration Assay
4. Quantification of the Proliferation Index of Human Dermal Fibroblast Cultures with the ArrayScan™ High-Content Screening Reader
5. An Automated Image Capture and Quantitation Approach to Identify Proteins Affecting Tumor Cell Proliferation
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