Compacted DNA Nanoparticles Administered to the Nasal Mucosa of Cystic Fibrosis Subjects Are Safe and Demonstrate Partial to Complete Cystic Fibrosis Transmembrane Regulator Reconstitution-Reference-Cited by-同舟云学术

Compacted DNA Nanoparticles Administered to the Nasal Mucosa of Cystic Fibrosis Subjects Are Safe and Demonstrate Partial to Complete Cystic Fibrosis Transmembrane Regulator Reconstitution

Published:2004-12 Issue:12 Volume:15 Page:1255-1269
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Konstan Michael W.¹,Davis Pamela B.¹,Wagener Jeffrey S.²,Hilliard Kathleen A.¹,Stern Robert C.¹,Milgram Laura J.H.¹,Kowalczyk Tomasz H.³,Hyatt Susannah L.³,Fink Tamara L.³,Gedeon Christopher R.³,Oette Sharon M.³,Payne Jennifer M.³,Muhammad Osman³,Ziady Assem G.¹,Moen Robert C.³,Cooper Mark J.³

Affiliation:

1. Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH 44106.

2. Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80218.

3. Copernicus Therapeutics, Cleveland, OH 44106.

Publisher

Mary Ann Liebert Inc

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2004.15.1255

Reference79 articles.

1. A Phase I Study of Aerosolized Administration of tgAAVCF to Cystic Fibrosis Subjects with Mild Lung Disease

2. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial

3. Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.