A Unidirectional 96-Well Fluidic Culture Platform for Upstream Cell Dosing with Subsequent Downstream Nonlinear and Ascending Exposure Gradients for Real-Time and Cell-Based Toxicity Screening Environments-Reference-Cited by-同舟云学术

A Unidirectional 96-Well Fluidic Culture Platform for Upstream Cell Dosing with Subsequent Downstream Nonlinear and Ascending Exposure Gradients for Real-Time and Cell-Based Toxicity Screening Environments

Published:2021-12-01 Issue:4 Volume:7 Page:175-191
ISSN:2332-1512
Container-title:Applied In Vitro Toxicology
language:en
Short-container-title:Applied In Vitro Toxicology

Author:

John Bincy A.¹,Sloan David J.¹,Jensen Timothy C.¹,Ramaiahgari Sreenivasa C.²,End Peter³,Resh Gabrielle E.¹,McClelland Randall E.¹⁴^ORCID

Affiliation:

1. SciKon Innovation, Inc., Chapel Hill, North Carolina, USA.

2. National Toxicology Program Division, National Institute of Environmental Health Sciences, Durham, North Carolina, USA.

3. Novartis, Basel, Switzerland.

4. Azture, Inc., La Jolla, California, USA.

Publisher

Mary Ann Liebert Inc

Subject

Health, Toxicology and Mutagenesis,Medical Laboratory Technology,Toxicology

Link

https://www.liebertpub.com/doi/pdf/10.1089/aivt.2021.0006

Reference21 articles.

1. Drug safety testing paradigm, current progress and future challenges: an overview

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3. Phase II and Phase III attrition rates 2011–2012

4. Maximizing the outcome of early ADMET models: strategies to win the drug-hunting battles?

5. Microfluidic cell chips for high-throughput drug screening

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