Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria-Reference-Cited by-同舟云学术

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Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria

Published:1996-03 Issue:4 Volume:7 Page:551-563
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Stingl Georg¹,Bröcker E.-B.²,Mertelsmann R.³,Wolff K.¹,Schreiber S.¹,Kämpgen E.²,Schneeberger A.¹,Dummer W.²,Brennscheid U.³,Veelken H.³,Bimstiel M. L.⁴,Zatloukal K.⁵,Schmidt W.⁴,Maass G.⁴,Wagner E.⁶,Buschle M.⁶,Giese M.⁶,Kempe E.-R.⁷,Weber H. A.⁷,Voigt T.⁷

Affiliation:

1. University of Vienna, Austria

2. University of Würzburg, Germany

3. University of Freiburg, Germany

4. Institute of Molecular Pathology, Vienna, Austria

5. University of Graz, Austria

6. Bender & Co., Vienna, Austria

7. Boehringer Ingelheim, Germany

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.1996.7.4-551

Reference54 articles.

1. Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.

2. Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes.

3. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.

4. Costimulation of T cells for tumor immunity

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