Impurities in Oligonucleotide Drug Substances and Drug Products-Reference-Cited by-同舟云学术

Impurities in Oligonucleotide Drug Substances and Drug Products

Published:2017-12 Issue:6 Volume:27 Page:309-322
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Capaldi Daniel¹,Teasdale Andy²,Henry Scott¹,Akhtar Nadim²,den Besten Cathaline³,Gao-Sheridan Samantha⁴,Kretschmer Matthias⁴,Sharpe Neal⁵,Andrews Ben⁶,Burm Brigitte⁷,Foy Jeffrey⁸

Affiliation:

1. Ionis Pharmaceuticals, Inc., Carlsbad, California.

2. AstraZeneca UK Ltd., Macclesfield, United Kingdom.

3. ProQR Therapeutics NV, Leiden, the Netherlands.

4. Alnylam Pharmaceuticals, Inc., Cambridge, Massachusetts.

5. Anavex Life Sciences Corp., New York, New York.

6. GlaxoSmithKline, Stevenage, United Kingdom.

7. ISA Therapeutics, Leiden, the Netherlands.

8. Celgene Corp., Summit, New Jersey.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/nat.2017.0691

Reference55 articles.

1. Clinical Expert Panel on Monitoring Potential Lung Toxicity of Inhaled Oligonucleotides: Consensus Points and Recommendations

2. Oligo Safety Working Group Exaggerated Pharmacology Subcommittee Consensus Document

3. Assessing unintended hybridization-induced biological effects of oligonucleotides

4. Recommendations for Safety Pharmacology Evaluations of Oligonucleotide-Based Therapeutics

5. Considerations for Assessment of Reproductive and Developmental Toxicity of Oligonucleotide-Based Therapeutics

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