Measuring the Impact of Genetic Heterogeneity and Chromosomal Inversions on the Efficacy of CRISPR-Cas9 Gene Drives in Different Strains of Anopheles gambiae

Author:

Pescod Poppy1ORCID,Bevivino Giulia2,Anthousi Amalia134,Shelton Ruth1,Shepherd Josephine1,Lombardo Fabrizio2,Nolan Tony1ORCID

Affiliation:

1. Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Greece.

2. Division of Parasitology, Department of Public Health and Infectious Diseases, University of Rome “la Sapienza,” Rome, Italy; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Greece.

3. Department of Biology, University of Crete, Heraklion, Crete, Greece; and Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Greece.

4. Department of Insects and Vector Borne Diseases, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Greece.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Biotechnology

Reference70 articles.

1. 1. World Health Organization. World Malaria Report 2022. WHO: Geneva; 2022.

2. Residual Malaria: Limitations of Current Vector Control Strategies to Eliminate Transmission in Residual Foci

3. 3. World Health Organization. Evaluation of Genetically Modified Mosquitoes for the Control of Vector-Borne Diseases. WHO: Geneva; 2020.

4. World Trade Report 2020

5. Site-specific selfish genes as tools for the control and genetic engineering of natural populations

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