Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1-Reference-Cited by-同舟云学术

Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1

Published:2024 Issue:3 Volume:70 Page:176-179
ISSN:2310-6905
Container-title:Biomeditsinskaya Khimiya
language:ru
Short-container-title:BIOMED KHIM

Author:

Nuzhnova A.A.¹,Kostina M.I.¹,Blazhenko A.A.²

Affiliation:

1. Anichkov Department of Neuropharmacology, Institute of Experimental Medicine, St. Petersburg, Russia; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia

2. Anichkov Department of Neuropharmacology, Institute of Experimental Medicine, St. Petersburg, Russia; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, St. Petersburg, Russia

Abstract

The effect of a synthetic analog of kisspeptin 1, a peptide involved in the regulation of the hypothalamicpituitary- gonadal (HPG) stress axis, on the cortisol level of Danio rerio fish was investigated. Kisspeptin 1 was administered at doses of 2 μg/kg and 8 μg/kg followed by resting for 1 h and 4 h. We found that kisspeptin at doses of 2 μg/kg and 8 μg/kg increased cortisol levels, with a significant spike in cortisol levels at 1 h post-injection.

Publisher

Institute of Biochemistry

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