The role of sarcopenia in the development of non-alcoholic fatty liver disease

Author:

Grinevich V. B.1ORCID,Sas E. I.1ORCID

Affiliation:

1. Military Medical Academy named after S. M. Kirov

Abstract

Currently, a large number of studies have been published supplementing our knowledge of sarcopenia and its effect on the development of metabolic disorders, including the formation of NAFLD. This data allows a new look at the pharmacological and non-pharmacological approaches to the treatment of NAFLD, based on basic physiological processes, including the biological axis of the muscle — the liver. This provides a compelling rationale for studying skeletal muscle as the main therapeutic target for NAFLD and metabolic syndrome.

Publisher

LLC Global Media Technology

Subject

Gastroenterology,Hepatology

Reference20 articles.

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2. Bedogni G., Miglioli L., Masutti F. et al. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology. 2005. No.42, pp. 44–52

3. Vilar-Gomez E., Martinez-Perez Y., Calzadilla-Bertot L. et al. Weight Loss via Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis. Gastroenterology. 2015. No. 42, pp. 44–52

4. Hong H. C., Hwang S. Y., Choi H. Y. et al. Relationship between sarcopenia and nonalcoholic fatty liver disease: the Korean Sarcopenic Obesity Study. Hepatology. 2014; 59: 1772–1778.

5. Lim S., Kim J. H., Yoon J. W. et al. Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA). Diabetes Care. 2010. No. 33, pp. 1652–1654.

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