Metformin in the prevention of colorectal cancer with diabetes mellitus-Reference-Cited by-同舟云学术

Metformin in the prevention of colorectal cancer with diabetes mellitus

Published:2022-10-07 Issue:9 Volume: Page:161-170
ISSN:1682-8658
Container-title:Experimental and Clinical Gastroenterology
language:
Short-container-title:jour

Author:

Druk I. V.¹^ORCID,Lyalyukova E. A.¹,Fadeeva E. A.¹^ORCID

Affiliation:

1. Omsk State Medical University of the Ministry of Health of the Russian Federation

Abstract

The purpose of the review is to present an analysis of current literature data on the prospects of using the oncoprotective effect of metformin in colorectal cancer. Metformin is a drug with a long history, it is a first-line drug for the treatment of type 2 diabetes mellitus (DM2), as well as the most commonly prescribed drug worldwide. Modern researches show that in addition to its role in glucose control, metformin can reduce the risk and mortality from some malignancies and improve the response of patients with DM2 to certain types of cancer treatment. Accumulated data indicate that metformin could be a candidate drug for drug prevention of colorectal cancer.

Publisher

LLC Global Media Technology

Subject

Gastroenterology,Hepatology

Reference67 articles.

1. Cimmerman Ya. S. Colorectal cancer: state-of-the-art. RJGHC. 2012. Vol. 22 no. 4, pp.5-16. (In Russian) @@Tsimmerman Ya. S. Kolorektal'nyi rak: sovremennoe sostoyanie problemy. Rossiiskii zhurnal gastroenterologii, gepatologii, koloproktologii, 2012. 22;4: C. 5-16.

2. Ferlay J., Colombet M., Soerjomataram I., et al. the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods.Int J Cancer. 2019 Apr 15;144(8):1941-1953. doi: 10.1002/ijc.31937.

3. Biller L.H., Schrag D. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review. JAMA. 2021;325(7):669-685. doi:10.1001/jama.2021.0106.

4. Kaprin A. D., Starinskij V. V., Shahzadova A. O. Sostoyanie onkologicheskoj pomoshchi naseleniyu Rossii v 2019 godu [The state of oncological care to the population of Russia in 2019], 2020. (In Russian) Available at: https://glavonco.ru/cancer_register/Pomoshch'%202019.pdf @@Kaprin A. D., Starinskii V. V., Shakhzadova A. O. Sostoyanie onkologicheskoi pomoshchi naseleniyu Rossii v 2019 godu, 2020. https://glavonco.ru/cancer_register/Pomoshch'%202019.pdf

5. Siegel R.L., Miller K. D., Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019 Jan;69(1):7-34. doi: 10.3322/caac.21551.