Recent Understanding and Future Directions in the Application of MMP-2 in Encapsulating Peritoneal Sclerosis Clinical Practice
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Published:2023
Issue:4
Volume:52
Page:359-365
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ISSN:0253-5068
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Container-title:Blood Purification
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language:en
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Short-container-title:Blood Purif
Author:
Fang Yaxuan,Chen Xin,Zhong Ke,Ni Qingying,He Zhenyang,Qiao Yanheng,Zhao Yanru,Li Jie,Yang Hongtao,Yang Bo
Abstract
Encapsulating peritoneal sclerosis (EPS) is an uncommon and harmful complication which may cause destructive outcomes. Matrix metalloproteinase-2 (MMP-2) as a protease can reduce constituents of the extracellular matrix and play a crucial role in the progression of EPS. As a new biomarker, MMP-2 may improve the detection rate of EPS patients in clinical work. In this review, we summarize the recent study of MMP-2 in different etiologies and the assessment of its application value and draw attention to its future directions.
Subject
Nephrology,Hematology,General Medicine