Insulin resistance profile as an indicator for Incidence of thyroid cancer-Reference-Cited by-同舟云学术

Insulin resistance profile as an indicator for Incidence of thyroid cancer

Published:2023-09-15 Issue:3 Volume:8 Page:1-10
ISSN:1390-9347
Container-title:Bionatura
language:
Short-container-title:RB

Author:

eda Hussein Ali, R¹,ameel Thamer Sanaa J²,Kasim Suker Dhamia²,Hameed Abbood Majid³,Al-Tuma Rafid R.⁴,Al-Mansouri Loma⁵

Affiliation:

1. PhD student, Physiology/Biology Department, College of Sciences, Basrah University, Iraq

2. Biology Department, College of Sciences, Basrah University, Iraq

3. Al Zahraa College of Medicine, Basrah University, Iraq

4. Basrah Nuclear Medicine Center. Iraq

5. College of Medicine University of Basrah. Iraq

Abstract

Thyroid nodules are commonly prevalent in human populations and have global concerns due to the high raped increase during the last decades. Some of them have malignant potential and cause life-threatening. The prospective cross-sectional study was conducted on 104 persons with thyroid nodules (25 with thyroid cancer and 79 samples were benign lesions) in Basrah, Iraq, from November 2019 to April 2022. To investigate the association of insulin resistance, Glucose, insulin hormone and obesity on thyroid cancer, Results: the thyroid cancer samples have higher serum levels of metabolic parameters, insulin hormone, Glucose, and insulin resistance (HOMA-IR) than benign samples, the male samples have a significant difference in HOMA-IR than females in all samples (malignant and benign samples), No substantial difference has been observed in BMI between thyroid cancer and harmless subjects; Conclusions: the serum metabolic parameters, insulin hormone, Glucose, and HOMA-IR play a vital role in future as an indicator for the diagnosis of thyroid cancer (papillary carcinoma) due to their increased levels in thyroid cancer samples than benign samples, no clear association between obesity and thyroid cancer incidence. Keywords: Metabolic parameters; Insulin resistance; Glucose; Insulin hormone; Thyroid cancer; Homa -IR

Publisher

Clinical Biotec

Subject

Infectious Diseases,Applied Microbiology and Biotechnology,Epidemiology,Biotechnology

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