Post-injection necrosis of femoral soft tissues induced by diclofenac, nonsteroidal anti-inflammatory drug (clinical case)

Author:

Atoian V. A.1ORCID,Fadeev M. F.1,Zolotov A. S.1,Zinkova E. A.1,Geltser B. I.1

Affiliation:

1. Far Eastern Federal University

Abstract

Nikolau syndrome is a rare post-injection complication with unclear etiology and pathogenesis, characterized by the development of acute local pain syndrome, localized erythematous rash, livedoid and hemorrhagic skin lesions with foci of ischemic necrosis. The paper presents a clinical case of Nikolau syndrome induced by intramuscular administration of diclofenac solution as an analgesic after hip replacement. The analysis of the causes, clinical picture and stages of treatment of post-injection complication was carried out.

Publisher

Pacific State Medical University

Subject

General Medicine

Reference10 articles.

1. Nicolau S. Dermite livédoide et gangréneuse de la fesse consécutive aux injections intramusculaires dans la syphilis. Ann Mal Vener. 1925;20:321–39.

2. Hamilton B, Fowler P, Galloway H, Popovic N. Nicolau syndrome in an athlete following intra-muscular diclofenac injection. Acta Orthop Belg. 2008;74:860–4.

3. Kim KK, Chae DS. Nicolau syndrome: A literature review. World J Dermatol. 2015;4(2):103–7. doi: 10.5314/wjd.v4.i2.103

4. Kilic İ, Kaya F, Özdemir AT, Demirel T, Celik I. Nicolau syndrome due to diclofenac sodium (Voltaren®) injection: a case report. J Med Case Reports. 2014;8(404). doi: 10.1186/17521947-8-404

5. Harde V, Schwarz T. Embolia cutis medicamentosa following subcutaneous injection of glatiramer acetate. J Dtsch Dermatol Ges. 2007;5:1122–3.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3