Amyloidosis Cutis Dyschromica, a Rare Cause of Hyperpigmentation: A New Case and Literature Review

Author:

Kuseyri Oya1,Haas Dorothea1,Lang Nina2,Schäkel Knut2,Bettendorf Markus1

Affiliation:

1. Department of General Pediatrics and Division of Pediatric Endocrinology and Diabetes, University Children’s Hospital Heidelberg, Heidelberg, Germany; and

2. Department of Dermatology, University of Heidelberg, Heidelberg, Germany

Abstract

Amyloidosis cutis dyschromica is a rare form of primary cutaneous amyloidosis without systemic involvement and characterized by asymptomatic, progressive hyper- and hypopigmentation. We present the first case of a patient with amyloidosis cutis dyschromica diagnosed previously elsewhere as having Addison disease with generalized hyperpigmentation of the skin. This case suggests that in patients presenting with asymptomatic cutaneous dyschromia a skin biopsy for histopathological examination should be considered.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology, and Child Health

Reference12 articles.

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3. Amyloidosis cutis dyschromica. DNA repair reduction in the cellular response to UV light.;Moriwaki;Arch Dermatol,1992

4. A clinical variety of localized cutaneous amyloidosis characterized by dyschromia (amyloidosis cutis dyschromica).;Morishima;Jpn J Dermatol B,1970

5. Amyloidosis cutis dyschromica.;Qiao;Orphanet J Rare Dis,2012

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