Successful Treatment of Refractory Autoimmune Hepatitis With Rituximab-Reference-Cited by-同舟云学术

Successful Treatment of Refractory Autoimmune Hepatitis With Rituximab

Published:2013-08-01 Issue:2 Volume:132 Page:e526-e530
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

D’Agostino Daniel¹,Costaguta Alejandro²,Álvarez Fernando³

Affiliation:

1. Pediatric Gastroenterology-Hepatology Division, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina;

2. Unidad de Hígado y Trasplante Hepático, Sanatorio de Niños, Rosario, Argentina; and

3. Pédiatrie, CHU Sainte-Justine Université de Montréal, Montreal, Canada

Abstract

Autoimmune hepatitis is a severe liver disease in which ∼10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/132/2/e526/1091242/peds_2011-1900.pdf

Reference12 articles.

1. Autoimmune hepatitis.;Krawitt;N Engl J Med,2006

2. Meeting report: International Autoimmune Hepatitis Group.;Johnson;Hepatology,1993

3. Autoimmune hepatitis and primary sclerosing cholangitis.;Alvarez;Clin Liver Dis,2006

4. The effect of rituximab on humoral and cell mediated immunity and infection in the treatment of autoimmune diseases.;Cooper;Br J Haematol,2010

5. Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis.;Muratori;Gut,1998

Cited by 61 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. KASL clinical practice guidelines for management of autoimmune hepatitis 2022;Clinical and Molecular Hepatology;2023-07-01

2. IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis;JHEP Reports;2023-07

3. Heterogeneity of antibody-secreting cells infiltrating autoimmune tissues;Frontiers in Immunology;2023-02-21

4. Open challenges in the management of autoimmune hepatitis;Minerva Gastroenterology;2023-02

5. Antidepressants cheer up hepatic B1 B cells: Hope for the treatment of autoimmune liver diseases?;Frontiers in Immunology;2023-01-17