SUDDEN UNEXPECTED DEATH IN INFANCY AND VIRAL INFECTION

Author:

Balduzzi Piero C.1,Greendyke Robert M.1

Affiliation:

1. Department of Microbiology and Pathology, University of Rochester School of Medicine and Dentistry, Strong Memorial Unit of the Monroe County Health Department Laboratories, and The Office of the Medical Examiner, County of Monroe, Rochester, New York

Abstract

The relationship between sudden, unexpected death of infants and enteric viruses was investigated. A total of 97 cases of sudden deaths and 33 "control" cases, comparable from several points of view, were studied. One viral strain was found in the stool of a "control" case and 14 agents were isolated from the sudden death group; 9 strains were found in stools and 5 strains, all Coxsackie B, were isolated from organ tissues obtained at necropsy. While this last finding suggests that enteric viruses may cause sudden deaths, the frequency of isolation is too low to be significant in a sample of the size investigated here.

Publisher

American Academy of Pediatrics (AAP)

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1. Enterovirus and parechovirus infections;Remington and Klein's Infectious Diseases of the Fetus and Newborn Infant;2025

2. Enteroviruses, Parechoviruses, and Saffold Viruses;Feigin and Cherry's Textbook of Pediatric Infectious Diseases;2025

3. Rates of Sudden Unexpected Infant Death Before and During the COVID-19 Pandemic;JAMA Network Open;2024-09-26

4. Evidence for an association of interferon gene variants with sudden infant death syndrome;International Journal of Legal Medicine;2019-01-08

5. High-Risk Pregnancy;2017-11-15

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