Affiliation:
1. Pirogov Russian National Research Medical University; National Medical Research Center of Endocrinology, Ministry of Public Health of Russia
2. National Medical Research Center of Endocrinology, Ministry of Public Health of Russia; Kazan (Privolzhsky) Federal University
3. Povolzhskiy State University of Physical Culture, Sports and Tourism
4. Povolzhskiy State University of Physical Culture, Sports and Tourism; Kazan State Medical University
5. Kazan (Privolzhsky) Federal University
Abstract
Purpose of the study: the aim of that study was an investigation of the level of adipokines, myokines and growth factors in the blood of athletes involved in acyclic sports — martial arts.Materials and methods: we have investigated 15 male athletes aged 15–19 years. The control group included 15 healthy men of the same age who did not engage in sports. In the blood serum of the all subjects, leptin, adiponectin, resistin, apelin, irisin, adipsin, myostatin, FGF21, osteocrin and oncostatin were determined using a multiplex analysis.Results: studies have shown that long-term regular martial arts training is accompanied by a decrease in the level of leptin, resistin and oncostatin M in the blood of athletes and a change in correlations between the content of the studied myokines, adipokines and growth factors compared with their values in the control group.Conclusions: regular long-term martial arts training is accompanied by a decrease in the level of leptin, resistin and oncostatin M in the blood of athletes. Their occurrence is associated with changes in the state of regulatory systems that control the production and secretion of myokines, adipokines and growth factors in adipose, muscle, nervous and bone tissue. The resulting shifts ensure adaptation of the athletes’ bodies to physical activity.
Publisher
National Alliance of Medicine and Sports - Healthy Generation
Reference36 articles.
1. Vasyukova O.V., Kasyanova Yu.V., Okorokov P.L., Bezlepkina O.B. Myokines and adipomyokines: inflammatory mediators or unique molecules of targeted therapy for obesity? Problems of Endocrinology. 2021;67(4):36–45. (In Russ.). https://doi.org/10.14341/probl12779
2. Orlov S.N., Kapilevich L.V., Dyakova E.Yu., Zakharova A.N., Kabachkova A.V., Kalinnikova Yu.G., et al. Skeletal muscles as an endocrine organ. Tomsk: Publishing House of Tomsk State University; 2018. (In Russ.).
3. Liu S., Cui F., Ning K., Wang Z., Fu P., Wang D., Xu H. Role of irisin in physiology and pathology. Front. Endocrinol. (Lausanne). 2022;13:962968. https://doi.org/10.3389/fendo.2022.962968
4. Shen S., Liao Q., Chen X., Peng C., Lin L. The role of irisin in metabolic flexibility: Beyond adipose tissue browning. Drug Discov. Today. 2022;27(8):2261–2267. https://doi.org/10.1016/j.drudis.2022.03.019
5. Pereira S., Cline D.L., Glavas M.M., Covey S.D., Kieffer T.J. Tissue-Specific Effects of Leptin on Glucose and Lipid Metabolism. Endocr. Rev. 2021;42(1):12–28. https://doi.org/10.1210/endrev/bnaa027