Apolipoprotein E Genetic Testing in a New Age of Alzheimer Disease Clinical Practice
Author:
Affiliation:
1. UC Irvine Institute for Memory Impairments and Neurological Disorders (MR, SAS); Department of Neurobiology and Behavior (MR); Department of Neurology (SAS); and Department of Psychiatry and Human Behavior, University of California, Irvine.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Neurology (clinical)
Link
https://www.neurology.org/doi/pdfdirect/10.1212/CPJ.0000000000200230
Reference40 articles.
1. Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
2. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
3. Association of apolipoprotein E allele 4 with late-onset familial and sporadic Alzheimer's disease
4. Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
5. Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
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