Affiliation:
1. Almazov National Medical Research Centre
Abstract
Currently, prostate cancer (PC) is one of the most common malignant neoplasms in men. More than 400,000 cases of prostate cancer are diagnosed annually in the world; in a number of countries, it occupies the second or third place in the structure of oncological diseases. A promising technology for the diagnosis and treatment of oncological diseases in nuclear medicine is radiotheranostics as an integrated approach that combines diagnostics and therapy using a single chemical molecule, but different ratioisotopes. For prostate cancer, the diagnostic radioisotope 68Ga and the therapeutic isotopes — 177Lu and 225Ac are used. The article discusses modern technologies for the production of radiopharmaceuticals for the diagnosis and radionuclide treatment of prostate cancer using theranostic pairs based on 68Ga/177Lu isotopes, as well as the prospects for the synthesis of new therapeutic radiopharmaceuticals labeled with the 177Lu isotope.
Publisher
Arterialnaya Gipertenziya
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