Breathing disorders during sleep in children with Prader-Willy syndrome

Abstract

Prader-Willi syndrome is the most common genetic disease causing life-threatening obesity in childhood, the pathogenesis of which is based on hypothalamic dysfunction. These children are at risk for developing a full range of sleep disorders, including sleep-related breathing disorders. The article presents a series of observations of children of different ages with Prader-Willi syndrome and various types of sleep breathing disorders, describes the possibilities of correction and their limitations.